• A 10% weight loss can improve fatty liver and possibly inflammation.
  • Metformin and ursodeoxycholic acid (UDCA) are not recommended.
  • Statins are safe in patients with fatty liver but whether they can reduce fatty liver is not known.
  • Omega-3 fatty acids have been tried.
  • Pioglitazone is useful in the treatment of biopsy-proven fatty liver with inflammation.
  • Vitamin E at a dose of 800 IU/day improves liver inflammation.
  • Use of bariatric surgery for treatment of fatty liver is premature and should be avoided in patients with cirrhosis.