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Dr K K Aggarwal

Triphala can help in reducing bronchial hyperreactivity

By Dr K K Aggarwal
Filed Under Wellness | Tagged With: , | | Comments Off on Triphala can help in reducing bronchial hyperreactivity

Triphala (TRP), a herbal extract, has been shown to affect lymphocytes and natural killer T (NKT) cell function. It has been shown to ameliorate bronchial hyperreactivity through immune–cell modulations.

In a study carried out at the Division of Allergy, Immunology and Pulmonary Medicine, Washington University in Saint Louis, Saint Louis, MO, asthma mouse models were generated through intraperitoneal (IP) injections of ovalbumin (OVA)/2 weeks followed by repeated intranasal OVA challenges.

Mice were then treated with normal saline (OVA/NS) or Triphala (OVA/TRP). Data were compared with mice treated with inhaled budesonide.

Both TRP and budesonide significantly ameliorated functional and histological OVA–induced bronchial hyperreactivity. Triphala causes a significant decrease in bronchial reactivity. It alters immune–cell distributions and show antioxidative properties. Immune–cell modulation with triphala can ameliorate lung injury.

(Ref: Horani A, Shoseyov D, Ginsburg I, et al. Triphala (PADMA) extract alleviates bronchial hyperreactivity in a mouse model through liver and spleen immune modulation and increased anti-oxidative effects. Ther Adv Respir Dis 2012 Aug;6(4):199–210).

Triphala can help in reducing bronchial hyperreactivity

By Dr K K Aggarwal
Filed Under Wellness | Tagged With: , , | | Comments Off on Triphala can help in reducing bronchial hyperreactivity

Triphala (TRP), a herbal extract, has been shown to affect lymphocytes and natural killer T (NKT) cell function. It has been shown to ameliorate bronchial hyperreactivity through immune–cell modulations. In a study carried out at the Division of Allergy, Immunology and Pulmonary Medicine, Washington University in Saint Louis, Saint Louis, MO, asthma mouse models were generated through intraperitoneal (IP) injections of ovalbumin (OVA)/2 weeks followed by repeated intranasal OVA challenges. Mice were then treated with normal saline (OVA/NS) or Triphala (OVA/TRP). Data were compared with mice treated with inhaled budesonide.
Both TRP and budesonide significantly ameliorated functional and histological OVA–induced bronchial hyperreactivity. Triphala causes a significant decrease in bronchial reactivity. It alters immune–cell distributions and show antioxidative properties. Immune–cell modulation with triphala can ameliorate lung injury.
(Ref: Horani A, Shoseyov D, Ginsburg I, et al. Triphala (PADMA) extract alleviates bronchial hyperreactivity in a mouse model through liver and spleen immune modulation and increased anti-oxidative effects. Ther Adv Respir Dis 2012 Aug;6(4):199–210).

Triphala can help in reducing bronchial hyperreactivity

By Dr K K Aggarwal
Filed Under Wellness | Tagged With: , , | | Comments Off on Triphala can help in reducing bronchial hyperreactivity

Triphala (TRP), a herbal extract, has been shown to affect lymphocytes and natural killer T (NKT) cell function. It has been shown to ameliorate bronchial hyperreactivity through immune–cell modulations.

In a study carried out at the Division of Allergy, Immunology and Pulmonary Medicine, Washington University in Saint Louis, Saint Louis, MO, asthma mouse models were generated through intraperitoneal (IP) injections of ovalbumin (OVA)/2 weeks followed by repeated intranasal OVA challenges.

Mice were then treated with normal saline (OVA/NS) or Triphala (OVA/TRP). Data were compared with mice treated with inhaled budesonide. Both TRP and budesonide significantly ameliorated functional and histological OVA–induced bronchial hyperreactivity.

Triphala causes a significant decrease in bronchial reactivity. It alters immune-cell distributions and show anti–oxidative properties. Immune–cell modulation with triphala can ameliorate lung injury.

(Ref: Horani A, Shoseyov D, Ginsburg I, et al. Triphala (PADMA) extract alleviates bronchial hyperreactivity in a mouse model through liver and spleen immune modulation and increased anti–oxidative effects. Ther Adv Respir Dis 2012 Aug;6(4):199–210).